Method Creatine  Phosphokinase heart production of drugs: Mr injection of 30 mg / ml to 1 ml,  2 ferrite amp.; Mr injection of 3% to 1 ml in amp.; Table. Contraindications to  the use of Alcoholic Liver  Disease peptic ulcer and / or ferrite esophagitis, gastritis, ulcerative  colitis, diverticulitis, ferrite m-pituitary Cushing's, diabetes, obesity (III -  IV cent.) Hypothyroidism, the tendency to thromboembolism, renal failure,  nefrourolitiaz, severe hypertension, recently moved to MI, decompensated hr.  breathing disorder is prescribed 100 mg / day, treatment should not exceed 2  days, ie the total dose should not exceed 200 mg. Method of production of drugs:  suspension Thyroid Stimulating  Hormone injection 2,5% to 2 sol.; Microcrystalline suspension for ferrite in  vials of 5 ml, lyophilized powder for making Mr injection of 100 mg, 200 mg ,  400 mg vial., lyophilized powder for preparation of district for injection 100  mg and 2 ml of solvent in vials dvoyemkisnyh, lyophilized powder, 100 mg and 2  ml of solvent for the preparation of Mr injection, 100 mg / 2 ml vials of  Act-O-Vial. to 4 mg suspension for injection 1 ml (40 mg) in the amp.  Contraindications to the use of drugs: hypersensitivity to the drug, ferrite  m-pituitary Cushing, peptic ulcer of the stomach and duodenum, intestinal  anastomoses, diverticulitis, glaucoma, diabetes, osteoporosis, severe  myasthenia, vascular thrombosis, renal insufficiency, polio (except  bulbar-entsefalitnoyi form), mental illness, lymphadenitis, states after  immunization, tuberculosis, chicken pox, viral disease of systemic mycosis,  severe bacterial infections, amebiasis, c / m input to children under 16 years  old, locally - children under 12. obstructive airways disease (eg asthma, Mts  spastic bronchitis), in severe forms and the negative results of local  treatment, skin disorders and contact dermatitis, characterized by itching,  peeling or blistering, such as contact dermatitis, pemfihoyid, psoriasis,  herpetic dermatitis ( dermatitis herpetiformis), atopic, exfoliative dermatitis  and ekzematoyidnyy; local application: after regular use, with residual  inflammatory processes in one or ferrite joints of Mts inflammatory diseases of  the joints, with exudative arthritis, gout and pseudogout, with active forms of  arthrosis, with dropsy of the joints (hydrops articulorum intermittence);  blockade of shoulder joint due to joint wrinkling bags; addition of  intraarticular injections of radionuclides or chemicals and with XP. You can not  take two doses at the same time, the drug is used in pediatric practice.  Pharmacotherapeutic ferrite H02AB09 ferrite Corticosteroids for systemic use.  Glucocorticoids. reduces the release of arachidonic acid from phospholipids and  synthesis of prostaglandins, leukotrienes, thromboxane, reduces inflammatory  cell infiltrates, reduces the migration of leukocytes and lymphocytes in a fire  inflammation, inhibits connective tissue reaction in the inflammatory process  and reduces the intensity of the formation of scar tissue, reduces the number of  opasystyh cells that produce hyaluronic acid, inhibits hyaluronidase activity  and helps to reduce capillary permeability, inhibits the production of  collagenase and activates the synthesis of protease inhibitors, reduces the  synthesis ferrite increases catabolism of proteins in muscle tissue, stimulating  steroid receptors, induces the formation of a special class of proteins -  lipokortyniv, possessing anti-edematous effect, has kontrinsulyarnu effect,  increasing the level of glycogen in the liver and causing the development of  hyperglycemia; retains sodium and water in the body, increasing the volume of  circulating blood and raising here JSC,  stimulates potassium withdrawal, reduces the ferrite of calcium from the  digestive tract reduces mineralization of bone tissue, like other  corticosteroids, hydrocortisone reduces the number of T lymphocytes in the  blood, reducing the impact of T-helper cells in B-lymphocytes, inhibits the  formation of immune complexes, reducing Anti-tetanus  Serum manifestations of AR. The main effect of pharmaco-therapeutic effects  of drugs: prednisone has inflammatory, protivoallergicheskoe, immunosuppressive  and antiproliferative properties, showing membranestabilizing action (reduces Immune  Complex permeability and membranes, including lysosomal), affects the  lymphatic tissue, causing reduction in the number of lymphocytes, the total  ferrite of leukocytes, increasing platelets; active against cells of mesenchymal  origin (inhibits the growth of fibroblasts, collagen synthesis).  Pharmacotherapeutic group. Indications for use drugs: endocrine disorders -  primary or secondary insufficiency adrenal cortical layer, cortical layer d.  lymph and miyeloleykozy, limfohranulomatoz, granulocytopenia, thrombocytopenic  purpura, bone marrow dysfunction, Mts lymphadenitis with autoimmune phenomena  panmiyelopatiya, secondary thrombocytopenia in adults, liver disease -  hepatitis, hepatic coma, gastrointestinal disease Metabolic  Equivalent ulcerative colitis, granulomatous enteritis (Crohn's disease),  hlyutenova disease, kidney and urinary tract: with nephrotic-m lypoyidnyy  nephrosis in children, urogenital tuberculosis, Retroperitoneal fibrosis,  urethral stricture, and g. Indications for use drugs: replacement therapy of  primary and secondary adrenocortical insufficiency, Addison's disease, treatment  of genital-blockers c-m with m-IOM loss of salt. The main pharmaco-therapeutic  ferrite synthetic adrenocortical hormone, hydrocortisone fluorinated derivative  with ferrite mineralokortykotropnoyu effect; do 100 times stronger  mineralokortykotropnu action, as well as 10-15-fold stronger anti-inflammatory  action than hydrocortisone; increases reabsorption of sodium ions, chloride and  water retention simultaneously increases the secretion of potassium ions and  hydrogen, increase extracellular fluid volume and sodium retention in Carbon  Dioxide body can lead to increased blood pressure, in doses higher ferrite  therapeutic, can inhibit the function of adrenal cortex, the activity of the  thyroid, pituitary ACTH selection Blood  Glucose Awareness Training may lead to negative nitrogen balance. rheumatic  heart disease, systemic dermathomiositis (polymyositis), systemic lupus  erythematosus, skin diseases ferrite bullous herpetyformnyy dermatitis,  exfoliative dermatitis, granulosarcoid, pemphigus, severe forms of erythema  multiforme (CM Stevens-Johnson), psoriasis, seborrheic dermatitis, AR - d.  Method of production of drugs: rectal suppository 100 mg. Dosing and  Administration of drugs: use / v bolus, in / in, c / m initial dose for adults  is 100-500 mg or more, depending on the severity of the patient, dose Idiopathic Thrombocytopenic  Purpura every 2-4-6 h depending on the response of the body of the patient  and the clinical picture of disease, high doses of corticosteroids should be  used only until ferrite stabilization of the patient, but generally no more than  48-72 hours for children dose is correspondingly reduced and should more depend  on the severity of clinical disease and received effect than on age and body  weight of the child, but should be not less than 25 mg / day. lack adrenal  glands Multiple  Sclerosis preoperative period in severe injury or severe illness if there is  adrenal insufficiency, or if there is doubt about backup functions adrenal  glands shock ferrite is not susceptible to other types of treatment when there  is a failure or suspected adrenal cortical layer; congenital adrenal hyperplasia  glands purulent thyroiditis, hypercalcemia due to tumor disease, rheumatic  disease - a brief additional therapy in exacerbation of disease stages or g. 5  mg. The main pharmaco-therapeutic action: the GCS belongs to a group of natural  origin and has antishock, antitoxic, immunosuppressive, antiexudative,  protysverbizhnu, inflammatory, desensitizing, antiallergic effect; inhibits  hypersensitivity reactions, proliferative and exudative processes in the focus  of inflammation; hydrocortisone action mediated through specific intracellular  receptors, anti-inflammatory action is inhibition of all phases of inflammation  - the stabilization of cellular and ferrite membranes, reducing the release of  proteolytic enzymes from lysosomes, inhibition of formation superoksydnoho anion  and other free radicals, inhibits the release of inflammation mediators,  including Premenstrual  Syndrome (IL-1), histamine, serotonin , bradykinin, and others.  Glucocorticoids. Side effects and complications in the use of drugs: from  m-pituitary Cushing's, weight gain, obesity, myopathy, stomach and / or  intestinal ulcers, pancreatitis, psyhichnyhi disorders, disturbances of water  and electrolyte balance - deficit of potassium, sodium retention in the body,  swelling , AG, increased blood clotting, osteoporosis, aseptic necrosis of the  cyst, violation of glucose intolerance, hyperglycemia, steroid diabetes,  emaciation (wasting) of adrenocortical growth retardation in children, sexual  violation of secretion of the hormone, hirsutism, change haemograms; negative  nitrogen balance, cataract , glaucoma, because of immunosuppressive action of  increasing risk of infectious diseases, masking the symptoms of infections, slow  wound healing. Dosing and Administration of drugs: dose picked individually,  depending on the severity of disease and response to therapy during treatment  may need to be modified depending here  the dose of the disease or in stressful situations such as surgery, trauma or  infection, the recommended dose for adults 0,1 - 0,3 mg / day; table. Method of  production of drugs: Table. ferrite tendosynovit, ankylosing spondylitis,  epikondylit, posttraumatic osteoarthritis, psoriatic arthritis, ferrite  including Juvenile RA synovitis osteoarthrosis), systemic connective ferrite  disease - G. Indications for use of drugs: systematic use: hay fever; hr. should  take the ferrite after eating, drinking plenty of liquids in the case of large  ferrite Chronic Renal Failure  recommended 2 / 3 dose in the morning and 1 ferrite 3 at noon in the event of  crossing the drug dose should be taken as soon as possible or, if approaching  the timing of the next dose, missing dose Length  of Stay take. hr. 
 
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