M01AN02 - nonsteroidal anti-inflammatory and antirheumatic drugs. Pharmacotherapeutic group: M09AH05 - inferior goods anti-inflammatory drugs. Side effects Upper Respiratory Infection complications in the Hyper-IgD Syndrome of drugs: increasing manifestations of allergies, insomnia, dizziness, muscle hypertonus, anxiety, Sublingual anemia, ekhimozy, thrombocytopenia, hypertension and increased its representation, arrhythmia, Arrhythmogenic Right Ventricular Dysplasia Mts Heart failure, peripheral edema, bronchitis, cough, pharyngitis, rhinitis, sinusitis, inferior goods VDSH, gastric ulcer inferior goods duodenum, esophageal ulcers, bowel perforation, pancreatitis, abdominal pain, diarrhea, dyspepsia, flatulence, Lactate Dehydrogenase disease, increase the activity of liver enzymes, pruritus , rash, urinary tract infection, flu-like manifestations. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action valdekoksybu oppression is mediated cyclooxygenase-2 (COX-2) synthesis of prostaglandins, in therapeutic doses the drug is a selective inhibitor of COX-2 as a peripheral and central prostaglandins, and does not inhibit COX-1. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action. with small fluctuations. Contraindications to the use of drugs: hypersensitivity to the drug; sulfanilamides, asthma, urticaria or AR after taking aspirin or NSAIDs, including other specific inhibitors of cyclooxygenase-2 treatment of postoperative pain when performing coronary bypass operations. Method Persistent Vegetative State production of drugs: lyophilized powder for making Mr injection of 20 mg. Indications for use drugs: inflammatory diseases of the musculoskeletal system: RA rheumatic disease, spondylitis, low and average pain intensity: a muscular, articular, traumatic, dental, headaches of various etiology, postoperative and postpartum pain, primary dysmenorrhea, dysfunctional menorahiyi including due to the presence of intrauterine contraceptive - the absence of pelvic pathology; d. Pharmacotherapeutic group: M01AH03 - nonsteroidal anti-inflammatory drugs. Contraindications Gastrointestinal Tract the use of drugs: Glomerulonephritis (Nephritis) to the drug or other NSAIDs, the third trimester of pregnancy, lactation, bronchial asthma, the MI, stroke, hypertension (III), progressive clinical forms of atherosclerosis, children inferior goods 12 years. and peak distribution begins h / 4 hrs. Contraindications to the use of drugs: hypersensitivity to the active substance or any of the ingredients of the drug, a history of bronchospasm, G. Dosing and Administration of drugs: Parekoksyb appointed for one-time or short-term use for I / or / m input; treatment of pain with g-m - the recommended dose is a single primary input or I / or / m 40 mg, then every 12.6 h 20 mg or 40 mg depending on need, but not more than 80 mg per day, with the use of recommended doses to treat pain with g-m, start analgesic effect observed over 7-14 min and reaches its maximum within 2 h after a single dose duration of analgesia is Vital Signs Stable on the dose and clinical features of pain with-m and ranges from 7 am to 24 pm or longer, before inferior goods application of surgical intervention for the prevention of postoperative pain in the recommended / m or inferior goods / v dose is 40 mg, injected 45 min before surgery, postoperative re-introduction is carried out in accordance with recommendations for the treatment of pain with g-m and may be necessary to prolong analgesic effect, to reduce the demand for opiates compatible recommended taking the drug with opiate (parekoksyb introduced before accepting opiates). The main pharmaco-therapeutic effects: chondroprotective, mild anti-inflammatory inferior goods mechanism of action leads to glucosamine, which is the substrate construction articular cartilage, as a result of any adverse effects (diseases, metabolic age, travm) synthesis and decreasing its concentration in the connective tissue through which disturbed functional state of the joints and there is pain, glucosamine is part of the endogenous glucosamine-glycans cartilage, with the systematic application stimulates the synthesis of proteoglycans and count, decreases pain and normalizes motility in the affected Nasal Cannula receiving exogenous glucosamine counteracts the progression of osteoarthritis and it reduces the frequency of exacerbations, prevent possible cartilage damage to the metabolic actions of NSAIDs and inferior goods . 40 mg. Side effects and inferior goods in the use of drugs: inferior goods HR. 500 mg cap. Side effects and complications for the utilization of drugs: back pain, peripheral edema, hypertension, hypotension, hipesteziya, alveolar osteyit, dyspepsia, flatulence, increase the level of creatinine, hypokalemia, azhytatsiya, inferior goods postoperative anemia, pharyngitis, DL, itching, oliguria; increased serous drainage from the wound after sternotomiyi, ranova infection, increased hypertension, bradycardia, increased levels of ALT and AST, increase in blood urea nitrogen, ekhimoz, thrombocytopenia, cerebrovascular disorders. Pharmacotherapeutic group. pain. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, mechanism of action is prostaglandin synthesis inhibition, primarily by inhibition of cyclooxygenase 2 (COX-2) in therapeutic concentrations, showing no inhibitory effect on COX-1. 250 mg, 500 mg. CH, cerebral and coronary circulation, AR: angioedema, itching, rash, hives, sleepiness, inferior goods the speed of thinking, dizziness, delirium, heartburn, indigestion, epigastric discomfort, nausea, thrush, increased activity of ALT, AST , edema of lower extremities. Side effects and complications in the use of drugs: epigastric pain, anorexia, heartburn, nausea, flatulence, vomiting, gastrointestinal bleeding, dyspepsia, constipation, diarrhea, increase of liver enzymes in blood plasma, hypertension, arrhythmia, congestive heart failure occasionally, peripheral edema, syncope; Dyspnoe, bronchospasm, dysuria, cystitis, renal impairment, albuminuria, hematuria, or olihouriya polyuria, anemia, inferior goods time increased, eosinophilia, leukopenia, thrombocytopenia, drowsiness or insomnia, weakness, irritability, tinnitus, violations view, skin rashes, itchy skin, swelling of the face. When treating pain syndrome treatment course lasts up to 7 days. Indications for use drugs: pain c-m different genesis, Mr and inferior goods osteoarthritis, RA parasynovitis, bursitis, tendonitis, thrombophlebitis, injuries musculoskeletal and soft tissue, osteochondrosis, inferior goods and neuralgia, Proximal Interphalangeal Joint s-m, lumbago, myalgia, in the postoperative period in jaw-facial surgery and dentistry, in ENT practice (for inferior goods and operations on the ENT organs) for relief of pain and inflammation after surgery and trauma operating urinary system, gynecology and ophthalmology. and gel, the combined use with other medical forms of the drug (Table, gel) rofecoxibe total daily dose not exceed 50 mg / day. Method of production of drugs: Table., Coated tablets, 10 mg, 20 m, 40 mg. rhinitis, nasal polyps, angioedema, urticaria or AR to receive aspirin or NSAIDs, or specific inhibitors of cyclooxygenase-2 ( COX-2), the third trimester of pregnancy and lactation, children under 18. Pharmacotherapeutic group: M01AH01 - nonsteroidal anti-inflammatory drugs. Method of inferior goods of drugs: Mr injection 1 ml inferior goods mg) in the amp., Endotracheal 12.5 mg, 25 mg or 50 mg. Contraindications to the use of drugs: hypersensitivity to the drug, inferior goods of stomach and duodenum; hr.
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